Cargando…

Joint mimicking mechanical load activates TGFβ1 in fibrin‐poly(ester‐urethane) scaffolds seeded with mesenchymal stem cells

Transforming growth factor‐β1 (TGF‐β1) is widely used in an active recombinant form to stimulate the chondrogenic differentiation of mesenchymal stem cells (MSCs). Recently, it has been shown that the application of multiaxial load, that mimics the loading within diarthrodial joints, to MSCs seeded...

Descripción completa

Detalles Bibliográficos
Autores principales: Gardner, Oliver F. W., Fahy, Niamh, Alini, Mauro, Stoddart, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191646/
https://www.ncbi.nlm.nih.gov/pubmed/27445107
http://dx.doi.org/10.1002/term.2210