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Joint mimicking mechanical load activates TGFβ1 in fibrin‐poly(ester‐urethane) scaffolds seeded with mesenchymal stem cells
Transforming growth factor‐β1 (TGF‐β1) is widely used in an active recombinant form to stimulate the chondrogenic differentiation of mesenchymal stem cells (MSCs). Recently, it has been shown that the application of multiaxial load, that mimics the loading within diarthrodial joints, to MSCs seeded...
Autores principales: | Gardner, Oliver F. W., Fahy, Niamh, Alini, Mauro, Stoddart, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191646/ https://www.ncbi.nlm.nih.gov/pubmed/27445107 http://dx.doi.org/10.1002/term.2210 |
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