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Elucidation of the interplay between Fe(II), Fe(III), and dopamine with relevance to iron solubilization and reactive oxygen species generation by catecholamines

The non‐enzymatically catalyzed oxidation of dopamine (DA) and the resultant formation of powerful oxidants such as the hydroxyl radical ((•) OH) through ‘Fenton chemistry’ in the presence of iron within dopaminergic neurons are thought to contribute to the damage of cells or even lead to neuronal d...

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Detalles Bibliográficos
Autores principales: Sun, Yingying, Pham, A. Ninh, Waite, T. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191651/
https://www.ncbi.nlm.nih.gov/pubmed/26991725
http://dx.doi.org/10.1111/jnc.13615