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Evaluating Uncertainty in Signaling Networks Using Logical Modeling

Systems biology studies the structure and dynamics of biological systems using mathematical approaches. Bottom-up approaches create models from prior knowledge but usually cannot cope with uncertainty, whereas top-down approaches infer models directly from data using statistical methods but mostly n...

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Detalles Bibliográficos
Autores principales: Thobe, Kirsten, Kuznia, Christina, Sers, Christine, Siebert, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191669/
https://www.ncbi.nlm.nih.gov/pubmed/30364151
http://dx.doi.org/10.3389/fphys.2018.01335