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Accelerated RNA secondary structure design using preselected sequences for helices and loops

Nucleic acids can be designed to be nano-machines, pharmaceuticals, or probes. RNA secondary structures can form the basis of self-assembling nanostructures. There are only four natural RNA bases, therefore it can be difficult to design sequences that fold to a single, specified structure because ma...

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Detalles Bibliográficos
Autores principales: Bellaousov, Stanislav, Kayedkhordeh, Mohammad, Peterson, Raymond J., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191713/
https://www.ncbi.nlm.nih.gov/pubmed/30097542
http://dx.doi.org/10.1261/rna.066324.118