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Perspectives on topology of the human m(1)A methylome at single nucleotide resolution

N(1)-methyladenosine was recently reported to be a chemical modification in mRNA. However, while we identified hundreds of m(1)A sites in the human transcriptome in a previous work, others have detected only nine sites in cytosolic and mitochondrial mRNAs. Herein, we provide additional evidence that...

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Detalles Bibliográficos
Autores principales: Xiong, Xushen, Li, Xiaoyu, Wang, Kun, Yi, Chengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191714/
https://www.ncbi.nlm.nih.gov/pubmed/30131401
http://dx.doi.org/10.1261/rna.067694.118