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Molecular mechanism of substrate recognition and specificity of tRNA(His) guanylyltransferase during nucleotide addition in the 3′–5′ direction
The tRNA(His) guanylyltransferase (Thg1) transfers a guanosine triphosphate (GTP) in the 3′–5′ direction onto the 5′-terminal of tRNA(His), opposite adenosine at position 73 (A(73)). The guanosine at the −1 position (G(−1)) serves as an identity element for histidyl-tRNA synthetase. To investigate t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191723/ https://www.ncbi.nlm.nih.gov/pubmed/30111535 http://dx.doi.org/10.1261/rna.067330.118 |