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Characterization of recombinant OspA in two different Borrelia vaccines with respect to immunological response and its relationship to functional parameters

BACKGROUND: Prevention of Lyme disease in dogs in North America depends on effective vaccination against infection by the tick vector-born spirochete Borrelia burgdorferi. Most vaccines effectively prevent spirochete transmission to dogs during tick feeding based on immunization with the outer-surfa...

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Detalles Bibliográficos
Autores principales: Grosenbaugh, Deborah A, De Luca, Karelle, Durand, Pierre-Yves, Feilmeier, Bradley, DeWitt, Kristopher, Sigoillot-Claude, Cecile, Sajous, Marie-Line, Day, Michael J, David, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191903/
https://www.ncbi.nlm.nih.gov/pubmed/30326885
http://dx.doi.org/10.1186/s12917-018-1625-7