Cargando…

Characterization of recombinant OspA in two different Borrelia vaccines with respect to immunological response and its relationship to functional parameters

BACKGROUND: Prevention of Lyme disease in dogs in North America depends on effective vaccination against infection by the tick vector-born spirochete Borrelia burgdorferi. Most vaccines effectively prevent spirochete transmission to dogs during tick feeding based on immunization with the outer-surfa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grosenbaugh, Deborah A, De Luca, Karelle, Durand, Pierre-Yves, Feilmeier, Bradley, DeWitt, Kristopher, Sigoillot-Claude, Cecile, Sajous, Marie-Line, Day, Michael J, David, Frederic
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191903/ https://www.ncbi.nlm.nih.gov/pubmed/30326885 http://dx.doi.org/10.1186/s12917-018-1625-7

Ejemplares similares

OspA heterogeneity of Borrelia valaisiana confirmed by phenotypic and genotypic analyses
por: Ryffel, Karine, et al.
Publicado: (2003)

Borrelia burgdorferi OspA is an arthropod-specific transmission- blocking Lyme disease vaccine
Publicado: (1996)

Immune Response to Lactobacillus plantarum Expressing Borrelia burgdorferi OspA Is Modulated by the Lipid Modification of the Antigen
por: del Rio, Beatriz, et al.
Publicado: (2010)

Blocking pathogen transmission at the source: reservoir targeted OspA-based vaccines against Borrelia burgdorferi
por: Gomes-Solecki, Maria
Publicado: (2014)

OspA-CD40 dyad: ligand-receptor interaction in the translocation of neuroinvasive Borrelia across the blood-brain barrier
por: Pulzova, Lucia, et al.
Publicado: (2011)

The year that shaped the outcome of the OspA vaccine for human Lyme disease
por: Dattwyler, Raymond J., et al.
Publicado: (2022)

Essential Role for OspA/B in the Life Cycle of the Lyme Disease Spirochete
por: Yang, Xiaofeng F., et al.
Publicado: (2004)

Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4
por: van Burgel, Nathalie D, et al.
Publicado: (2010)

Two regulatory elements required for enhancing ospA expression in Borrelia burgdorferi grown in vitro but repressing its expression during mammalian infection
por: Xu, Qilong, et al.
Publicado: (2010)

The novel Lyme borreliosis vaccine VLA15 shows broad protection against Borrelia species expressing six different OspA serotypes
por: Comstedt, Pär, et al.
Publicado: (2017)

Establishment of a minor groove binder-probe based quantitative real time PCR to detect Borrelia burgdorferi sensu lato and differentiation of Borrelia spielmanii by ospA-specific conventional PCR
por: Strube, Christina, et al.
Publicado: (2010)

Immunization with a recombinant subunit OspA vaccine markedly impacts the rate of newly acquired Borrelia burgdorferi infections in client-owned dogs living in a coastal community in Maine, USA
por: Eschner, Andrew K, et al.
Publicado: (2015)

Evaluation of OspA Vaccination-Induced Serological Correlates of Protection against Lyme Borreliosis in a Mouse Model
por: Schwendinger, Michael G., et al.
Publicado: (2013)

Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development
por: Izac, Jerilyn R., et al.
Publicado: (2017)

Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine
Publicado: (1993)

An Inverted Repeat in the ospC Operator Is Required for Induction in Borrelia burgdorferi
por: Drecktrah, Dan, et al.
Publicado: (2013)

Investigation of ospC Expression Variation among Borrelia burgdorferi Strains
por: Xiang, Xuwu, et al.
Publicado: (2017)

BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi
por: Shi, Yanlin, et al.
Publicado: (2014)

Evolution and Distribution of the ospC Gene, a Transferable Serotype Determinant of Borrelia burgdorferi
por: Barbour, Alan G., et al.
Publicado: (2010)

Oral Immunization with OspC Does Not Prevent Tick-Borne Borrelia burgdorferi Infection
por: Melo, Rita, et al.
Publicado: (2016)

In Vivo Imaging Demonstrates That Borrelia burgdorferi ospC Is Uniquely Expressed Temporally and Spatially throughout Experimental Infection
por: Skare, Jonathan T., et al.
Publicado: (2016)

A Borrelia burgdorferi outer surface protein C (OspC) genotyping method using Luminex technology
por: Pearson, Patrick, et al.
Publicado: (2022)

Moduli space of topological osp(2|2)+osp(2|2) algebra
por: Ano, N
Publicado: (1995)

Lipoprotein succession in Borrelia burgdorferi: similar but distinct roles for OspC and VlsE at different stages of mammalian infection
por: Tilly, Kit, et al.
Publicado: (2013)

Possible effect of mutations on serological detection of Borrelia burgdorferi sensu stricto ospC major groups: An in-silico study
por: Mechai, Samir, et al.
Publicado: (2023)

osp(1|2) Conformal Field Theory
por: Ennes, I P, et al.
Publicado: (1997)

Multiplet shortening in Osp(N,4)
por: Freedman, Daniel Z, et al.
Publicado: (1984)

Singleton representations of Osp(N,4)
por: Nicolai, Hermann C, et al.
Publicado: (1984)

Invasive potential of Borrelia burgdorferi sensu stricto ospC type L strains increases the possible disease risk to humans in the regions of their distribution
por: Golovchenko, Maryna, et al.
Publicado: (2014)

Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi
por: Kolodziejczyk, Robert, et al.
Publicado: (2017)

Comparative analysis of antibody responses to outer surface protein (Osp)A and OspC in dogs vaccinated with Lyme disease vaccines
por: Camire, A.C., et al.
Publicado: (2021)

Inferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: A Study of OspC Proteins of Borrelia burgdorferi
por: Baum, Elisabeth, et al.
Publicado: (2013)

A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice
por: Sayeed, Md. Abu, et al.
Publicado: (2015)

Ecole d'Eté de Physique Théorique: Les Astres Occlus
por: DeWitt, Cécile F, et al.
Publicado: (1973)

Ecole d'Eté de Physique Théorique: Relativity, groups and topology
por: DeWitt, Cécile F, et al.
Publicado: (1964)

No-ghost theorem and OSp(1,1|2) in gauge theories
por: Niemi, Antti J
Publicado: (1989)

The Pursuit of Quantum Gravity: Memoirs of Bryce DeWitt from 1946 to 2004
por: DeWitt-Morette, Cécile
Publicado: (2011)

OSP(1/32) in 11 dimensions and relation to SO(8) supergravity
por: Chamseddine, A H
Publicado: (1980)

Shigella OspC3 suppresses murine cytosolic LPS sensing
por: Oh, Changhoon, et al.
Publicado: (2021)

The influence of OSPE and PBL on competency-based pharmacy student self-assessment
por: Dymek, Justyna, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sn6vej8ciq5kjcvt6vkgv102r1