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MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis

BACKGROUND: Currently, no suitable clinical marker for detection of septic immunosuppression is available. We aimed at identifying microRNAs that could serve as biomarkers of T-cell mediated immunoparalysis in sepsis. METHODS: RNA was isolated from purified T-cells or from whole blood cells obtained...

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Detalles Bibliográficos
Autores principales: Möhnle, P, Hirschberger, S, Hinske, L C, Briegel, J, Hübner, M, Weis, S, Dimopoulos, G, Bauer, M, Giamarellos-Bourboulis, E J, Kreth, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191918/
https://www.ncbi.nlm.nih.gov/pubmed/30332984
http://dx.doi.org/10.1186/s10020-018-0056-z