PD-1 deficiency is not sufficient to induce myeloid mobilization to the brain or alter the inflammatory profile during chronic neurodegeneration

Innate immune activation is a major driver of neurodegenerative disease and immune regulatory pathways could be potential targets for therapeutic intervention. Recently, Programmed cell death-1 (PD-1) immune checkpoint inhibition has been proposed to mount an IFN-γ-dependent systemic immune response...

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Detalles Bibliográficos
Autores principales: Obst, J., Mancuso, R., Simon, E., Gomez-Nicola, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191933/
https://www.ncbi.nlm.nih.gov/pubmed/30086399
http://dx.doi.org/10.1016/j.bbi.2018.08.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191933/
https://www.ncbi.nlm.nih.gov/pubmed/30086399
http://dx.doi.org/10.1016/j.bbi.2018.08.006

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