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Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands

To overcome the side effects of and resistance to cisplatin, a variety of Pt(IV) prodrugs were designed and synthesized via different modifications including combination with lipid chains to increase hydrophobicity, conjugation with short peptide chains or nanoparticles to improve drug delivery, or...

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Detalles Bibliográficos
Autores principales: Li, Xuejiao, Liu, Yahong, Tian, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191961/
https://www.ncbi.nlm.nih.gov/pubmed/30402082
http://dx.doi.org/10.1155/2018/8276139