TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Tumour-associated macrophages (TAMs) are abundant in many cancers, and often display an immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance to therapy. Yet macrophages are highly plastic and can also acquire an anti-tumourigenic M1-like phenotype. Here, we show th...

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Detalles Bibliográficos
Autores principales: Rodell, Christopher B., Arlauckas, Sean P., Cuccarese, Michael F., Garris, Christopher S., Li, Ran, Ahmed, Maaz S., Kohler, Rainer H., Pittet, Mikael J., Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192054/
https://www.ncbi.nlm.nih.gov/pubmed/31015631
http://dx.doi.org/10.1038/s41551-018-0236-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192054/
https://www.ncbi.nlm.nih.gov/pubmed/31015631
http://dx.doi.org/10.1038/s41551-018-0236-8

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