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Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Aberrant histone acetylation and deacetylation are increasingly thought to play important roles in the pathogenesis of rheumatoid arthritis (RA). However, limited data from studies about the activity of histone deacetylases (HDACs) and histone acetyltransferase (HAT) in RA are controversial. Those c...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhou, Mi, Lv, Xiuying, Song, Lina, Zhang, Di, He, Yan, Wang, Mian, Zhao, Xue, Yuan, Xiaoqing, Shi, Guixiu, Wang, Dashan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192092/
https://www.ncbi.nlm.nih.gov/pubmed/30402512
http://dx.doi.org/10.1155/2018/7313515