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PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury

Sepsis is a systemic inflammatory reaction caused by infection. Multiple organ failure ultimately leads to high morbidity and mortality. Unfortunately, therapies against these responses have been unsuccessful due to the insufficient underlying pathophysiological evidence. Protein interacting with C-...

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Detalles Bibliográficos
Autores principales: Mo, Yunchang, Lou, Yingying, Zhang, Anqi, Zhang, Jingjing, Zhu, Congying, Zheng, Bo, Li, Dan, Zhang, Mingyuan, Jin, Wenjun, Zhang, Lei, Wang, Junlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192133/
https://www.ncbi.nlm.nih.gov/pubmed/30402043
http://dx.doi.org/10.1155/2018/6757368