Diverse target gene modifications in Plasmodium falciparum using Bxb1 integrase and an intronic attB

Genetic manipulation of the human malaria parasite Plasmodium falciparum is needed to explore pathogen biology and evaluate antimalarial targets. It is, however, aggravated by a low transfection efficiency, a paucity of selectable markers and a biased A/T-rich genome. While various enabling technolo...

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Detalles Bibliográficos
Autores principales: Balabaskaran-Nina, Praveen, Desai, Sanjay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192176/
https://www.ncbi.nlm.nih.gov/pubmed/30333047
http://dx.doi.org/10.1186/s13071-018-3129-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192176/
https://www.ncbi.nlm.nih.gov/pubmed/30333047
http://dx.doi.org/10.1186/s13071-018-3129-5

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