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Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array

BACKGROUND: The capacity of technologies measuring DNA methylation (DNAm) is rapidly evolving, as are the options for applicable bioinformatics methods. The most commonly used DNAm microarray, the Illumina Infinium HumanMethylation450 (450K array), has recently been replaced by the Illumina Infinium...

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Detalles Bibliográficos
Autores principales: McEwen, Lisa M, Jones, Meaghan J, Lin, David Tse Shen, Edgar, Rachel D, Husquin, Lucas T, MacIsaac, Julia L, Ramadori, Katia E, Morin, Alexander M, Rider, Christopher F, Carlsten, Chris, Quintana-Murci, Lluís, Horvath, Steve, Kobor, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192219/
https://www.ncbi.nlm.nih.gov/pubmed/30326963
http://dx.doi.org/10.1186/s13148-018-0556-2