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Genetic variants in nuclear DNA along with environmental factors modify mitochondrial DNA copy number: a population-based exome-wide association study

BACKGROUND: Mitochondrial DNA (mtDNA) copy number has been found associated with multiple diseases, including cancers, diabetes and so on. Both environmental and genetic factors could affect the copy number of mtDNA. However, limited study was available about the relationship between genetic variant...

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Detalles Bibliográficos
Autores principales: Li, Zhihua, Zhu, Meng, Du, Jiangbo, Ma, Hongxia, Jin, Guangfu, Dai, Juncheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192277/
https://www.ncbi.nlm.nih.gov/pubmed/30326835
http://dx.doi.org/10.1186/s12864-018-5142-7