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MiR-133a Mimic Alleviates T1DM-Induced Systolic Dysfunction in Akita: An MRI-Based Study

Diabetic cardiomyopathy is a leading cause of heart failure. Developing a novel therapeutic strategy for diabetic cardiomyopathy and characterizing animal models used for diabetes mellitus (DM) are important. Insulin 2 mutant (Ins2(+/-)) Akita is a spontaneous, genetic, mouse model for T1DM, which i...

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Detalles Bibliográficos
Autores principales: Nandi, Shyam Sundar, Shahshahan, Hamid Reza, Shang, Quanliang, Kutty, Shelby, Boska, Michael, Mishra, Paras Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192327/
https://www.ncbi.nlm.nih.gov/pubmed/30364155
http://dx.doi.org/10.3389/fphys.2018.01275