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MicroRNA-302a/d inhibits the self-renewal capability and cell cycle entry of liver cancer stem cells by targeting the E2F7/AKT axis

BACKGROUND: There is increasing evidence that liver cancer stem cells (LCSCs) contribute to hepatocellular carcinoma (HCC) initiation and progression. MicroRNA (miRNA) plays a significant functional role by directly regulating respective targets in LCSCs-triggered HCC, however, little is known about...

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Detalles Bibliográficos
Autores principales: Ma, Yu-Shui, Lv, Zhong-Wei, Yu, Fei, Chang, Zheng-Yan, Cong, Xian-Ling, Zhong, Xiao-Ming, Lu, Gai-Xia, Zhu, Jian, Fu, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192354/
https://www.ncbi.nlm.nih.gov/pubmed/30326936
http://dx.doi.org/10.1186/s13046-018-0927-8