Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production

BACKGROUND: Vitamin D is a key immune-modulator that plays a role in the innate and adaptive immune systems. Certain pathogens impair the immune defense by downregulating the vitamin D receptor (VDR) pathway. Low serum levels of vitamin D are associated with increased hepatitis B virus (HBV) replica...

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Detalles Bibliográficos
Autores principales: Gotlieb, Neta, Tachlytski, Irena, Lapidot, Yelena, Sultan, Maya, Safran, Michal, Ben-Ari, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192355/
https://www.ncbi.nlm.nih.gov/pubmed/30326825
http://dx.doi.org/10.1186/s10020-018-0055-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192355/
https://www.ncbi.nlm.nih.gov/pubmed/30326825
http://dx.doi.org/10.1186/s10020-018-0055-0

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