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Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

BACKGROUND: Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in malignancy, invasion and chemoresistance between cancer types and subtypes. Mi...

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Detalles Bibliográficos
Autores principales: MacDonald, Julie A., Kura, Niharika, Sussman, Carleigh, Woods, Dori C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192357/
https://www.ncbi.nlm.nih.gov/pubmed/30326924
http://dx.doi.org/10.1186/s13048-018-0463-3