Efficacy of exogenous pyruvate in Trembler(J) mouse model of Charcot‐Marie‐Tooth neuropathy

INTRODUCTION: Classic Charcot‐Marie‐Tooth (CMT) neuropathies including those with Schwann cell genetic defects exhibit a length‐dependent process affecting the distal axon. Energy deprivation in the distal axon has been the proposed mechanism accounting for length‐dependent distal axonal degeneratio...

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Detalles Bibliográficos
Autores principales: Sahenk, Zarife, Yalvac, Mehmet E., Amornvit, Jakkrit, Arnold, William David, Chen, Lei, Shontz, Kimberly M., Lewis, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192403/
https://www.ncbi.nlm.nih.gov/pubmed/30239155
http://dx.doi.org/10.1002/brb3.1118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192403/
https://www.ncbi.nlm.nih.gov/pubmed/30239155
http://dx.doi.org/10.1002/brb3.1118

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