Class-B CpG-ODN Formulated With a Nanostructure Induces Type I Interferons-Dependent and CD4(+) T Cell-Independent CD8(+) T-Cell Response Against Unconjugated Protein Antigen

There is a need for new vaccine adjuvant strategies that offer both vigorous antibody and T-cell mediated protection to combat difficult intracellular pathogens and cancer. To this aim, we formulated class-B synthetic oligodeoxynucleotide containing unmethylated cytosine-guanine motifs (CpG-ODN) wit...

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Detalles Bibliográficos
Autores principales: Chiodetti, Ana L., Sánchez Vallecillo, María F., Dolina, Joseph S., Crespo, María I., Marin, Constanza, Schoenberger, Stephen P., Allemandi, Daniel A., Palma, Santiago D., Pistoresi-Palencia, María C., Morón, Gabriel, Maletto, Belkys A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192457/
https://www.ncbi.nlm.nih.gov/pubmed/30364187
http://dx.doi.org/10.3389/fimmu.2018.02319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192457/
https://www.ncbi.nlm.nih.gov/pubmed/30364187
http://dx.doi.org/10.3389/fimmu.2018.02319

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