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Genetic Correlation Profile of Schizophrenia Mirrors Epidemiological Results and Suggests Link Between Polygenic and Rare Variant (22q11.2) Cases of Schizophrenia

New methods in genetics research, such as linkage disequilibrium score regression (LDSR), quantify overlap in the common genetic variants that influence diverse phenotypes. It is becoming clear that genetic effects often cut across traditional diagnostic boundaries. Here, we introduce genetic correl...

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Detalles Bibliográficos
Autores principales: Duncan, Laramie E, Shen, Hanyang, Ballon, Jacob S, Hardy, Kate V, Noordsy, Douglas L, Levinson, Douglas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192473/
https://www.ncbi.nlm.nih.gov/pubmed/29294133
http://dx.doi.org/10.1093/schbul/sbx174