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GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses

Higher vertebrates have evolved innate and adaptive immune systems to defend against foreign substances and pathogens. Sophisticated regulatory circuits are needed to avoid inappropriate immune responses and inflammation. GPR108 is a seven-transmembrane family protein that activates NF-κB strongly w...

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Detalles Bibliográficos
Autores principales:	Dong, Danfeng, Zhou, Haisheng, Na, Soon-Young, Niedra, Rasma, Peng, Yibing, Wang, Huajun, Seed, Brian, Zhou, Guo Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192633/ https://www.ncbi.nlm.nih.gov/pubmed/30332431 http://dx.doi.org/10.1371/journal.pone.0205303

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