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Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

The role of host genetic variation in the development of complicated Staphylococcus aureus bacteremia (SAB) is poorly understood. We used whole exome sequencing (WES) to examine the cumulative effect of coding variants in each gene on risk of complicated SAB in a discovery sample of 168 SAB cases (8...

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Detalles Bibliográficos
Autores principales: Scott, William K., Medie, Felix Mba, Ruffin, Felicia, Sharma-Kuinkel, Batu K., Cyr, Derek D., Guo, Shengru, Dykxhoorn, Derek M., Skov, Robert L., Bruun, Niels E., Dahl, Anders, Lerche, Christian J., Petersen, Andreas, Larsen, Anders Rhod, Lauridsen, Trine Kiilerich, Johansen, Helle Krogh, Ullum, Henrik, Sørensen, Erik, Hassager, Christian, Bundgaard, Henning, Schønheyder, Henrik C., Torp-Pedersen, Christian, Østergaard, Louise Bruun, Arpi, Magnus, Rosenvinge, Flemming, Erikstrup, Lise T., Chehri, Mahtab, Søgaard, Peter, Andersen, Paal S., Fowler, Vance G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192642/
https://www.ncbi.nlm.nih.gov/pubmed/30289878
http://dx.doi.org/10.1371/journal.pgen.1007667