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TMEM106B, a risk factor for FTLD and aging, has an intrinsically disordered cytoplasmic domain

TMEM106B was initially identified as a risk factor for FTLD, but recent studies highlighted its general role in neurodegenerative diseases. Very recently TMEM106B has also been characterized to regulate aging phenotypes. TMEM106B is a 274-residue lysosomal protein whose cytoplasmic domain functions...

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Detalles Bibliográficos
Autores principales:	Kang, Jian, Lim, Liangzhong, Song, Jianxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192649/ https://www.ncbi.nlm.nih.gov/pubmed/30332472 http://dx.doi.org/10.1371/journal.pone.0205856

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