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Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals

Recent advances in epigenomics have made it possible to map genome-wide regulatory regions using empirical methods. Subsequent comparative epigenomic studies have revealed that regulatory regions diverge rapidly between genome of different species, and that the divergence is more pronounced in enhan...

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Detalles Bibliográficos
Autores principales: Huh, Iksoo, Mendizabal, Isabel, Park, Taesung, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192654/
https://www.ncbi.nlm.nih.gov/pubmed/30289877
http://dx.doi.org/10.1371/journal.pcbi.1006451