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Targeting phosphatases of regenerating liver (PRLs) in cancer

The phosphatase of regenerating liver (PRL) family, also known as protein tyrosine phosphatase 4A (PTP4A), are dual-specificity phosphatases with largely unknown cellular functions. However, accumulating evidence indicates that PRLs are oncogenic across a broad variety of human cancers. PRLs are hig...

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Detalles Bibliográficos
Autores principales: Wei, Min, Korotkov, Konstantin V., Blackburn, Jessica S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192704/
https://www.ncbi.nlm.nih.gov/pubmed/29859177
http://dx.doi.org/10.1016/j.pharmthera.2018.05.014