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Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes
It is widely assumed that cells must be physically isolated to study their molecular profiles. However, intact tissue samples naturally exhibit variation in cellular composition, which drives covariation of cell-class-specific molecular features. By analyzing transcriptional covariation in 7221 inta...
Autores principales: | Kelley, Kevin W., Nakao-Inoue, Hiromi, Molofsky, Anna V., Oldham, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192711/ https://www.ncbi.nlm.nih.gov/pubmed/30154505 http://dx.doi.org/10.1038/s41593-018-0216-z |
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