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An enhanced RRM2 siRNA delivery to rheumatoid arthritis fibroblast-like synoviocytes through a liposome-protamine-DNA-siRNA complex with cell permeable peptides

Rheumatoid arthritis (RA) is considered to be a systemic autoimmune disease that induces systemic complications and progressive disability. It affects a large number of people. RA fibroblast-like synoviocytes (RA-FLS) promote the progression of RA through the secretion of proinflammatory cytokines a...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wang, Xueping, Sun, Jin, Fu, Shiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192755/
https://www.ncbi.nlm.nih.gov/pubmed/30106091
http://dx.doi.org/10.3892/ijmm.2018.3815