DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride

The aim of the present study was to determine the role of topoisomerase 1 (TOP1) and topoisomerase 2A (TOP2A) in liver cancer (LC), and to investigate the inhibitory effect of nitidine chloride (NC) on these two topoisomerases. Immunohistochemistry (IHC) staining and microarray or RNA sequencing dat...

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Detalles Bibliográficos
Autores principales: Liu, Li-Min, Xiong, Dan-Dan, Lin, Peng, Yang, Hong, Dang, Yi-Wu, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192772/
https://www.ncbi.nlm.nih.gov/pubmed/30132517
http://dx.doi.org/10.3892/ijo.2018.4531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192772/
https://www.ncbi.nlm.nih.gov/pubmed/30132517
http://dx.doi.org/10.3892/ijo.2018.4531

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