Cargando…

GPR17 mediates ischemia-like neuronal injury via microglial activation

GPR17 is a G (i)-coupled dual receptor, linked to P2Y and CysLT receptors stimulated by uracil nucleotides and cysteinyl leukotrienes, respectively. Recent evidence has demonstrated that GPR17 inhibition ameliorates the progression of cerebral ischemic injury by regulating neuronal death and microgl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Bing, Wang, Hao, Li, Cai-Xia, Song, Sheng-Wen, Fang, San-Hua, Wei, Er-Qing, Shi, Qiao-Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192776/ https://www.ncbi.nlm.nih.gov/pubmed/30226562 http://dx.doi.org/10.3892/ijmm.2018.3848

Ejemplares similares

Involvement of GPR17 in Neuronal Fibre Outgrowth
por: Braune, Max, et al.
Publicado: (2021)

Electroacupuncture attenuates myocardial ischemia-reperfusion injury by inhibiting microglial engulfment of dendritic spines
por: Zhang, Fan, et al.
Publicado: (2023)

PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons
por: Yan, Wei-Tao, et al.
Publicado: (2022)

Direct protection of cultured neurons from ischemia-like injury by minocycline
por: Huang, Wendy C., et al.
Publicado: (2010)

LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury
por: Wan, Peixing, et al.
Publicado: (2019)

Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin
por: Ren, Hongxia, et al.
Publicado: (2015)

Inflammation and JNK's Role in Niacin-GPR109A Diminished Flushed Effect in Microglial and Neuronal Cells With Relevance to Schizophrenia
por: Ansarey, Sabrina H.
Publicado: (2021)

Correction to: LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury
por: Wan, Peixing, et al.
Publicado: (2022)

The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation
por: Zhang, Zengli, et al.
Publicado: (2018)

Cangrelor ameliorates CLP-induced pulmonary injury in sepsis by inhibiting GPR17
por: Luo, Qiancheng, et al.
Publicado: (2021)

Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies
por: Kwon, Somin, et al.
Publicado: (2019)

Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells
por: Saliba, Soraya Wilke, et al.
Publicado: (2018)

DOK3 is involved in microglial cell activation in neuropathic pain by interacting with GPR84
por: Gao, Wen-Shuang, et al.
Publicado: (2020)

Vav1 promotes inflammation and neuronal apoptosis in cerebral ischemia/reperfusion injury by upregulating microglial and NLRP3 inflammasome activation
por: Qiu, Jing, et al.
Publicado: (2023)

Propofol Mediated Protection of the Brain From Ischemia/Reperfusion Injury Through the Regulation of Microglial Connexin 43
por: Zhang, Tingting, et al.
Publicado: (2021)

GPR88 in A(2A)R Neurons Enhances Anxiety-Like Behaviors
por: Meirsman, Aura Carole, et al.
Publicado: (2016)

Lomitapide ameliorates middle cerebral artery occlusion‐induced cerebral ischemia/reperfusion injury by promoting neuronal autophagy and inhibiting microglial migration
por: Zheng, Yangmin, et al.
Publicado: (2022)

Differential Regulation of Microglial Activation in Response to Different Degree of Ischemia
por: Gao, Hao, et al.
Publicado: (2022)

Natural Killer Cells in Hepatic Ischemia-Reperfusion Injury
por: Huang, Miao, et al.
Publicado: (2022)

CRNDE/ETS1/GPR17 Facilitates the Proliferation, Migration, and Invasion of Glioma
por: Hu, Yan, et al.
Publicado: (2021)

GPR68 Is a Neuroprotective Proton Receptor in Brain Ischemia
por: Wang, Tao, et al.
Publicado: (2020)

T cells modulate the microglial response to brain ischemia
por: Benakis, Corinne, et al.
Publicado: (2022)

Mib2 Deficiency Inhibits Microglial Activation and Alleviates Ischemia-Induced Brain Injury
por: Li, Xiaoheng, et al.
Publicado: (2020)

Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury
por: Goebel, Ulrich, et al.
Publicado: (2020)

Commentary on “PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons”
por: Arrázola, Macarena S., et al.
Publicado: (2022)

Microglial control of neuronal activity
por: Béchade, Catherine, et al.
Publicado: (2013)

Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits
por: Yu, Diankun, et al.
Publicado: (2022)

Synthesis and Ability of New Ligands for G Protein-Coupled Receptors 17 (GPR17)
por: Zhuo, Tongyou, et al.
Publicado: (2017)

Sevoflurane preconditioning ameliorates neuronal deficits by inhibiting microglial MMP-9 expression after spinal cord ischemia/reperfusion in rats
por: Li, Xiao-Qian, et al.
Publicado: (2014)

Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding
por: Reilly, Austin M., et al.
Publicado: (2019)

Activation of CCL21-GPR174/CCR7 on cardiac fibroblasts underlies myocardial ischemia/reperfusion injury
por: Meng, Xiao-Wen, et al.
Publicado: (2022)

Flavonoids in myocardial ischemia-reperfusion injury: Therapeutic effects and mechanisms
por: Jia, Jun-ying, et al.
Publicado: (2020)

TMEM16F Aggravates Neuronal Loss by Mediating Microglial Phagocytosis of Neurons in a Rat Experimental Cerebral Ischemia and Reperfusion Model
por: Zhang, Yijie, et al.
Publicado: (2020)

Upregulation of Neuronal Cylindromatosis Expression is Essential for Electroacupuncture-Mediated Alleviation of Neuroinflammatory Injury by Regulating Microglial Polarization in Rats Subjected to Focal Cerebral Ischemia/Reperfusion
por: Lin, Xing, et al.
Publicado: (2021)

Effects of a Novel GPR55 Antagonist on the Arachidonic Acid Cascade in LPS-Activated Primary Microglial Cells
por: Saliba, Soraya Wilke, et al.
Publicado: (2021)

Microglial TLR4 is Critical for Neuronal Injury and Cognitive Dysfunction in Subarachnoid Hemorrhage
por: Islam, Rezwanul, et al.
Publicado: (2022)

The Role of PGK1 in Promoting Ischemia/Reperfusion Injury-Induced Microglial M1 Polarization and Inflammation by Regulating Glycolysis
por: Cao, Wei, et al.
Publicado: (2023)

Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia
por: Cao, Qian, et al.
Publicado: (2023)

Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression
por: Li, Yizhi, et al.
Publicado: (2022)

Neuronal and microglial mechanisms of neuropathic pain
por: Zhuo, Min, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_fetr4ilpo7pfarpa8m7pgpghlj