Synergistic effect of ursodeoxycholic acid on the antitumor activity of sorafenib in hepatocellular carcinoma cells via modulation of STAT3 and ERK

Sorafenib has been approved for the treatment of advanced stage hepatocellular carcinoma but has limited efficacy. Ursodeoxycholic acid exerts cytoprotective activities in hepatocytes and is believed to suppress tumorigenesis through cell cycle arrest and induction of apoptosis. The present study ex...

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Detalles Bibliográficos
Autores principales: Lee, Seulki, Cho, Young Youn, Cho, Eun Ju, Yu, Su Jong, Lee, Jeong-Hoon, Yoon, Jung-Hwan, Kim, Yoon Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192782/
https://www.ncbi.nlm.nih.gov/pubmed/30106087
http://dx.doi.org/10.3892/ijmm.2018.3807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192782/
https://www.ncbi.nlm.nih.gov/pubmed/30106087
http://dx.doi.org/10.3892/ijmm.2018.3807

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