Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis

BACKGROUND & AIMS: Primary biliary cholangitis (PBC) is an autoimmune-associated chronic liver disease triggered by environmental factors, such as exposure to xenobiotics, which leads to a loss of tolerance to the lipoic acid-conjugated regions of the mitochondrial pyruvate dehydrogenase complex...

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Detalles Bibliográficos
Autores principales: Probert, Philip M., Leitch, Alistair C., Dunn, Michael P., Meyer, Stephanie K., Palmer, Jeremy M., Abdelghany, Tarek M., Lakey, Anne F., Cooke, Martin P., Talbot, Helen, Wills, Corinne, McFarlane, William, Blake, Lynsay I., Rosenmai, Anna K., Oskarsson, Agneta, Figueiredo, Rodrigo, Wilson, Colin, Kass, George E., Jones, David E., Blain, Peter G., Wright, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192827/
https://www.ncbi.nlm.nih.gov/pubmed/30006067
http://dx.doi.org/10.1016/j.jhep.2018.06.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192827/
https://www.ncbi.nlm.nih.gov/pubmed/30006067
http://dx.doi.org/10.1016/j.jhep.2018.06.027

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