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Lin(−)CCR2(+) hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade
Immune checkpoint blockade using anti-PD-1 monoclonal antibodies has shown considerable promise in the treatment of solid tumors, but brain tumors remain notoriously refractory to treatment. In CNS malignancies that are completely resistant to PD-1 blockade, we found that bone marrow-derived, lineag...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192988/ https://www.ncbi.nlm.nih.gov/pubmed/30333482 http://dx.doi.org/10.1038/s41467-018-06182-5 |