The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

The Cancer/Testes (CT) Antigen HORMAD1 is germ cell-restricted and plays developmental roles in generation and processing of meiotic DNA Double Strand Breaks (DSB). Many tumors aberrantly overexpress HORMAD1 yet the potential impact of this CT antigen on cancer biology is unclear. We tested a potent...

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Detalles Bibliográficos
Autores principales: Gao, Yanzhe, Kardos, Jordan, Yang, Yang, Tamir, Tigist Y., Mutter-Rottmayer, Elizabeth, Weissman, Bernard, Major, Michael B., Kim, William Y., Vaziri, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192992/
https://www.ncbi.nlm.nih.gov/pubmed/30333500
http://dx.doi.org/10.1038/s41598-018-33601-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192992/
https://www.ncbi.nlm.nih.gov/pubmed/30333500
http://dx.doi.org/10.1038/s41598-018-33601-w

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