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Loss of a conserved salt bridge in bacterial glycosyl hydrolase BgIM-G1 improves substrate binding in temperate environments
Salt bridges are the strongest electrostatic interactions in proteins. They substantially contribute to a protein’s structural stability. Thus, mutations of salt bridges are typically selected against. Here, we report on the evolutionary loss of a highly conserved salt bridge in the GH1 family glyco...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192996/ https://www.ncbi.nlm.nih.gov/pubmed/30345395 http://dx.doi.org/10.1038/s42003-018-0167-7 |