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Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs
Approximately 1500 RNA-binding proteins (RBPs) profoundly impact mammalian cellular function by controlling distinct sets of transcripts, often using sequence-specific binding to 3′ untranslated regions (UTRs) to regulate mRNA stability and translation. Aside from their individual effects, higher-or...
Autores principales: | Sternburg, Erin L., Estep, Jason A., Nguyen, Daniel K., Li, Yahui, Karginov, Fedor V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192998/ https://www.ncbi.nlm.nih.gov/pubmed/30333515 http://dx.doi.org/10.1038/s41598-018-33596-4 |
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