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HBV induces inhibitory FcRL receptor on B cells and dysregulates B cell-T follicular helper cell axis
Spontaneous or treatment induced seroconversion in chronic HBV infection is rare and generation of anti-HBs antibodies is the current goal of HBV therapeutics. Here we investigated B and follicular T helper (Tfh) cell defects that persist in HBV infection despite long-term nucleos(t)ide analog (NUC)...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193006/ https://www.ncbi.nlm.nih.gov/pubmed/30333570 http://dx.doi.org/10.1038/s41598-018-33719-x |