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Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness

Glioblastoma is a highly malignant tumor that easily acquires resistance to treatment. The stem-cell-like character (stemness) has been thought to be closely associated with the treatment resistance of glioblastoma cells. In this study, we determined that farnesyl diphosphate synthase (FDPS), a key...

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Detalles Bibliográficos
Autores principales: Kim, Hee Yeon, Kim, Dong Keon, Bae, Seung-Hyun, Gwak, HyeRan, Jeon, Ji Hoon, Kim, Jong Kwang, Lee, Byung Il, You, Hye Jin, Shin, Dong Hoon, Kim, Young-Ho, Kim, Soo Youl, Han, Sung-Sik, Shim, Jin-Kyoung, Lee, Ji-Hyun, Kang, Seok-Gu, Jang, Hyonchol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193020/
https://www.ncbi.nlm.nih.gov/pubmed/30333528
http://dx.doi.org/10.1038/s12276-018-0166-2