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MINA53 deficiency leads to glioblastoma cell apoptosis via inducing DNA replication stress and diminishing DNA damage response

MYC-induced nuclear antigen (MINA53) is a JmjC (jumonji C domain)-containing protein, which is highly expressed in many cancers including glioblastoma. We have revealed in our previous report that MINA53 is a poor prognostic indicator for glioblastoma patients, and knockdown of MINA53 could reduce g...

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Detalles Bibliográficos
Autores principales: Xuan, Fan, Huang, Mengying, Zhao, Erhu, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193027/
https://www.ncbi.nlm.nih.gov/pubmed/30333481
http://dx.doi.org/10.1038/s41419-018-1084-x