1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism

Herein we provide experimental proof that 1-oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism. The reactions reported are rapid, proceed under mild conditions, and afford nitrones in excellent yields.

Detalles Bibliográficos
Autores principales: Stoyanovsky, Anastas D., Stoyanovsky, Detcho A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193029/
https://www.ncbi.nlm.nih.gov/pubmed/30333514
http://dx.doi.org/10.1038/s41598-018-33639-w
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author Stoyanovsky, Anastas D.
Stoyanovsky, Detcho A.
author_facet Stoyanovsky, Anastas D.
Stoyanovsky, Detcho A.
author_sort Stoyanovsky, Anastas D.
collection PubMed
description Herein we provide experimental proof that 1-oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism. The reactions reported are rapid, proceed under mild conditions, and afford nitrones in excellent yields.
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spelling pubmed-61930292018-10-23 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism Stoyanovsky, Anastas D. Stoyanovsky, Detcho A. Sci Rep Article Herein we provide experimental proof that 1-oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism. The reactions reported are rapid, proceed under mild conditions, and afford nitrones in excellent yields. Nature Publishing Group UK 2018-10-17 /pmc/articles/PMC6193029/ /pubmed/30333514 http://dx.doi.org/10.1038/s41598-018-33639-w Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Stoyanovsky, Anastas D.
Stoyanovsky, Detcho A.
1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title_full 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title_fullStr 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title_full_unstemmed 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title_short 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
title_sort 1-oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-h n,n-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193029/
https://www.ncbi.nlm.nih.gov/pubmed/30333514
http://dx.doi.org/10.1038/s41598-018-33639-w
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