Transposon mutagenesis screen in mice identifies TM9SF2 as a novel colorectal cancer oncogene

New therapeutic targets for advanced colorectal cancer (CRC) are critically needed. Our laboratory recently performed an insertional mutagenesis screen in mice to identify novel CRC driver genes and, thus, potential drug targets. Here, we define Transmembrane 9 Superfamily 2 (TM9SF2) as a novel CRC...

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Detalles Bibliográficos
Autores principales: Clark, Christopher R., Maile, Makayla, Blaney, Patrick, Hellweg, Stefano R., Strauss, Anna, Durose, Wilaiwan, Priya, Sambhawa, Habicht, Juri, Burns, Michael B., Blekhman, Ran, Abrahante, Juan E., Starr, Timothy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193042/
https://www.ncbi.nlm.nih.gov/pubmed/30333512
http://dx.doi.org/10.1038/s41598-018-33527-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193042/
https://www.ncbi.nlm.nih.gov/pubmed/30333512
http://dx.doi.org/10.1038/s41598-018-33527-3

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