Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses. Here, we develop a reference strain-agnostic computa...

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Detalles Bibliográficos
Autores principales: Kavvas, Erol S., Catoiu, Edward, Mih, Nathan, Yurkovich, James T., Seif, Yara, Dillon, Nicholas, Heckmann, David, Anand, Amitesh, Yang, Laurence, Nizet, Victor, Monk, Jonathan M., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193043/
https://www.ncbi.nlm.nih.gov/pubmed/30333483
http://dx.doi.org/10.1038/s41467-018-06634-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193043/
https://www.ncbi.nlm.nih.gov/pubmed/30333483
http://dx.doi.org/10.1038/s41467-018-06634-y

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