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Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model

Variants near the ATP-binding cassette transporter A1 (ABCA1) gene are associated with elevated intraocular pressure and newly discovered risk factors for glaucoma. Previous studies have shown an association between ABCA1 deficiency and retinal inflammation. Using a mouse model of ischemia-reperfusi...

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Detalles Bibliográficos
Autores principales: Li, Lu, Xu, Lingjuan, Chen, Wei, Li, Xing, Xia, Qian, Zheng, Lu, Duan, Qiming, Zhang, Hong, Zhao, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193130/
https://www.ncbi.nlm.nih.gov/pubmed/30364320
http://dx.doi.org/10.3389/fncel.2018.00347