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Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model
Variants near the ATP-binding cassette transporter A1 (ABCA1) gene are associated with elevated intraocular pressure and newly discovered risk factors for glaucoma. Previous studies have shown an association between ABCA1 deficiency and retinal inflammation. Using a mouse model of ischemia-reperfusi...
Autores principales: | Li, Lu, Xu, Lingjuan, Chen, Wei, Li, Xing, Xia, Qian, Zheng, Lu, Duan, Qiming, Zhang, Hong, Zhao, Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193130/ https://www.ncbi.nlm.nih.gov/pubmed/30364320 http://dx.doi.org/10.3389/fncel.2018.00347 |
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