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Proteoliposome Engineering with Cell‐Free Membrane Protein Synthesis: Control of Membrane Protein Sorting into Liposomes by Chaperoning Systems

Integral membrane proteins (IMPs) modulate key cellular processes; their dysfunctions are closely related to disease. However, production of IMPs in active conformations for further study is hindered by aggregation and toxicity in living expression systems. IMPs are therefore produced in cell‐free s...

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Detalles Bibliográficos
Autores principales: Ando, Mitsuru, Schikula, Shun, Sasaki, Yoshihiro, Akiyoshi, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193158/
https://www.ncbi.nlm.nih.gov/pubmed/30356962
http://dx.doi.org/10.1002/advs.201800524