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Revision of the Structure and Total Synthesis of Topsentin C

An efficient synthetic approach to access (indol-3-yl)ethane-1,2-diamines with a protecting group at the indole N atom from readily available 3-(2-nitrovinyl)indoles is reported. This approach includes solvent-free conjugate addition of O -pivaloylhydroxylamines to 1-Boc-3-(2-nitrovinyl)indoles foll...

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Detalles Bibliográficos
Autores principales: Golantsov, Nikita E., Festa, Alexey A., Varlamov, Alexey V., Voskressensky, Leonid G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193241/
http://dx.doi.org/10.1055/s-0036-1588731